First Medical Publication. Cases & Observations, the first medical transactions published in the New World, was published in 1788 by the New Haven Medical Society. This publication afforded medical information to physicians, surgeons and hospitals and led to the first plan whereby doctors kept an actual case record of patients.

First Science Journal. The American Journal of Science was founded in 1830 by Benjamin Silliman of New Haven. Silliman is said to have been the most prominent and influential scientific man in America during the first half of the 19th century.

First Geography Book. In 1784 Meigs, Bowen and Dana, New Haven, published the first geography book in the U.S. Jedidiah Morse's 214-page book is called; Geography Made Easy: Being a Short, But Comprehensive System of that very Useful and Agreeable Science, Illustrated with Newly Constructed Maps, Adapted to the Capacities and Understanding of Children, Calculated Particularly for the Use and Improvement of Schools in the United States.

First Political History Book. In 1828 the first political history of the U.S. was written by Timothy Pitkin and published in New Haven.